Extend the range of Raman spectroscopy with THz-Raman®
Ondax’s patented THz-Raman® Spectroscopy Systems extend the range of traditional Raman spectroscopy into the terahertz/low-frequency regime, exploring the same range of energy transitions as terahertz spectroscopy – without limiting the ability to measure the fingerprint region. The THz-Raman spectral region covers both Stokes and anti-Stokes signals from ±5 cm-1 to 200 cm-1, (or 150 GHz to 6 THz), which contain important structural information about the molecule or crystal lattice. This region reveals a new “Structural Fingerprint” to complement the traditional “Chemical Fingerprint” of Raman, enabling simultaneous analysis of both molecular structure and chemical composition in one instrument for advanced materials characterization.
See What You’ve Been Missing More Data, Better Sensitivity and Reliability
THz-Raman spectra show clear differentiation of structural attributes of the material, ideal for identification and analysis of polymorphs, raw material sources, defects & contamination, crystal formation and orientation, phase monitoring and synthesis methods. Applications include pharmaceuticals, explosives, narcotics, nano- and bio-materials, semiconductors, photovoltaics, and petrochemicals.
By adding both low-frequency and anti-Stokes signals to the traditional fingerprint, THz-Raman systems boost overall Raman intensity and improve SNR.. And the symmetrical nature of the anti-Stokes signals act as a confirmation of Stokes peaks, while providing an inherent calibration reference that improves overall confidence and reliability.
One Sample, One System, One Answer
Combining both composition and structural analysis eliminates the need for multiple samples and instruments, lowering capital, training and maintenance costs. These compact plug-and-play platforms can be integrated with virtually any lab-grade microscope or Raman system. With excitation wavelengths ranging from 488nm to 976nm, and a wide range of options and compatible spectrometers to choose from, an Ondax THz-Raman® system can be optimized to match any application.
Plug-and-Play Upgrade To your existing microscope or Raman system, or configurable as a complete custom system
All TR-Series THz-Raman® modules are ultra-compact and simple to connect via fiber to almost any spectrometer or Raman system. A high-power, wavelength-stabilized, single-frequency laser source is precisely matched to the ultra narrow-band ASE, beamsplitter and notch filters to assure maximum throughput and exceptional attenuation (>OD 9) of the excitation source. Systems are available in 532nm, 633nm, 785nm, 808nm, 976nm and 1064nm excitation wavelengths.
The TR-PROBE is a compact, robust THz-Raman® probe that enables in-situ reaction or process monitoring, and can also be flexibly configured with a variety of sample interface accessories, including immersion or contact probe tips, a convenient vial/tablet holder, a Transmission Raman adapter, a microscope mount, or a steerable non-contact optic (see options below). A separate CleanLine™ laser provides ASE-free excitation via a multimode fiber, enabling the probe to operate in harsher environments where electrical connections are not permitted.
The TR-BENCH is configured for benchtop use and offers a similar range of interchangeable sample interface accessories holder for fast, easy measurements. The system also comes with a standard cage mounting plate (centered on the collimated output beam) to allow for customized collection optics or easy integration into a customized system. Options include circular polarization or a dual-port/dual polarization output for simultaneous measurement of both S and P polarizations.
The TR-MICRO mounts directly to a broad range of popular microscope platforms and micro-Raman systems, and can be easily switched in and out of the optical path. Linear polarization is standard, circular polarization is optional.
The TR-WPS Automated Well-plate Measurement System combines high throughput screening (HTS) capability with our patented low-frequency/THz-Raman® technology to automatically capture the entire Raman spectrum from -800 cm-1 to +2800 cm-1 for common well-plate measurements. Ideal for screening and identification of polymorphic compounds and co-crystals, or quantifying degree of crystallinity in pharmaceuticals,the WPS has been designed to be fully automated, from sample insertion to data generation. The sample is excited with a 785 nm Ondax CleanLine™ laser from below the well in an inverted microscope format. A plate auto-focusing system ensures measurement repeatability, and an integrated vision system with polarized light detection can be used to determine areas of interest within each well.
The WPSTM Application Software Interface has a highly intuitive GUI with a layered design, enabling fast learning and simplified operation, while providing extensive additional functionality in advanced mode.
- Polymorphic structure identification and monitoring
- Amorphous-to-crystalline transformation
- Structural studies of nano-and bio-materials
- In-situ Crystallization and Reaction Monitoring
- Trace detection and source attribution of explosives/hazmat/drugs
- Forensics studies
- Geological specimen analysis and gemology
- Fast collection of THz-Raman/Low frequency spectra
- Simultaneous Stokes and anti-Stokes signals improve SNR while providing inherent calibration reference
- High Optical Density (>OD8) with extremely high throughput
- Ultra-compact footprint, plug-and-play operation, fiber coupled output
- Compatible with most commercial spectrometers, microscopes and Raman systems
- Integrated ASE filtering with high-throughput 90/10 dichroic beamsplitter
- Available at 532, 633, 785, 850, 976nm, and 1064nm
Visit our Publications Page for more information on Low-frequency Raman Spectroscopy Applications
Download the Ondax Raman Products Brochure
Download the THz-Raman® PROBE System Datasheet
Download the THz-Raman®MICRO System Datasheet
Download the THz-Raman® BENCHTOP System Data Sheet
Download the SureBlock™ XLF Data Sheet
|Power at sample port (min)||mW||50 to 250*||100||300|
|* Specify power level at time of order|
|Spectral Range (typical)||-200cm-1 to +2200cm-1||0-1100 nm (w/Si Detector)|
|Spectral Resolution||2.5cm-1 to 4cm-1||1.25cm-1 or greater|